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Neurobiologics
- Overview
Neurobiologics is a neurosurgery specific version of
"Osteobiologics" technology. Osteobiologics
has become a synonym for the inclusion of biology and
biochemistry in the development of bone replacement
materials for muscular-skeletal healing. In neurosurgery,
it is used mainly in conditions involving the spinal
column. Mr. D'Urso utilitses neurobiological agents
like anit-fibrosis gel and bone growth factors in his
practice.
Anti-fibrosis Gel
Medtronic MediShield
MediShield is an adhesion barrier gel to prevent postoperative
adhesions from forming after back surgery. The gel is
an injectable, absorbable gel, in a 3mL syringe, for
use in reducing the incidence, extent and severity of
postsurgical adhesions following lumbar spine surgery.
Postsurgical adhesions are abnormal bands of scar tissue
that can form between tissues following surgery and
cause postoperative complications such as recurrent
back pain and weakness. The gel is placed in the epidural
space during laminectomy, laminotomy, and discectomy
procedures to separate tissues and act as a temporary,
protective barrier against adhesion formation.
Click here
to see the MediShield patient brochure.
Bone Growth Factors
The term "growth factor" refers to a naturally
occurring protein capable of stimulating cellular proliferation
and cellular differentiation. Growth factors are important
for regulating a variety of cellular processes. Growth
factors typically act as signaling molecules between
cells. Hormones are an example of growth factors. Growth
factors bind to specific receptors on the surface of
their target cells. They often promote cell differentiation
and maturation, which varies between growth factors.
For example, bone morphogenic proteins (BMPs) stimulate
bone cell differentiation, while vascular endothelial
growth factors stimulate blood vessel differentiation.
Click
here to download a document about bone growth factors
in spinal surgery.
Stryker OP-1 implant
OP-1 is a bone morphogenetic protein (BMP) that is
naturally found in the human body. This unique protein
has the ability to transform cells in the body to become
new bone and ultimately repair fractures.
Click
here to visit the OP-1 implant web site.
Medtronic INFUSE Bone Graft
INFUSE Bone Graft is a bone growth protein used in
an Anterior Lumbar Interbody Fusion (ALIF) procedure
in combination with a metallic cage implant.
Click
here to visit the INFUSE Bone Graft web site.
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